Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2499)
Related Products (2499)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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MED6-189
0 ImagesCat. No.: HY-169233CAS No.: 2650073-66-6MED6-189, a kalihinol analog, disrupts apicoplast function and vesicular trafficking in P. falciparum malaria (IC50 < 50 nM). MED6-189 targets the apicoplast, a nonphotosynthetic plastid found in most Apicomplexa parasites that is crucial for the synthesis of isoprenoids.
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Abierixin
0 ImagesCat. No.: HY-N13988CAS No.: 100634-16-0Abierixin has good anti-coccidial activity and weak antibacterial and ionophore activity.
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DDD100097
0 ImagesDDD100097 is a potent acyltransferase (TbNMT) inhibitor with an IC50 value of 2 nM. DDD100097 can significantly improve blood-brain barrier permeability. DDD100097 can be used in the study of African trypanosomiasis.
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Tripynadine
0 ImagesCat. No.: HY-127028CAS No.: 81849-98-1Synonyms: M-7204Tripynadine is an anti-malarial compound with oral activity.
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HAT-IN-9
0 ImagesCat. No.: HY-175979HAT-IN-9 (Compound 3F) is a selective proliferation inhibitor targeting Trypanosoma brucei. HAT-IN-9 inhibits the proliferation and division of Trypanosoma brucei. HAT-IN-9 is promising for research of African trypanosomiasis (HAT, i.e., sleeping sickness).
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Arprinocid-15N3
0 ImagesCat. No.: HY-W104379SArprinocid-15N3 is 15N3-labeled Arprinocid (HY-W104379). Arprinocid is a purine analog with activity against murine Toxoplasma gondii.
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Dimetridazole (Standard)
0 ImagesDimetridazole (Standard) is the analytical standard of Dimetridazole (HY-B1244). This product is intended for research and analytical applications. Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections.
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NEU617
0 ImagesCat. No.: HY-125084CAS No.: 1432450-82-2NEU617 is an anti-parasite agent. NEU617 inhibits the proliferation for the HAT (human African trypanosomiasis) pathogen (EC50: 42 nM for Trypanosoma brucei, 1.8 μM for T. cruzi). NEU617 is a derivative of Lapatinib (HY-50898).
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Benznidazole (Standard)
0 ImagesSynonyms: Benznidazol (Standard); Ro 07-1051 (Standard); Ro 71051 (Standard)Benznidazole (Standard) is the analytical standard of Benznidazole. This product is intended for research and analytical applications. Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.
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D44
0 ImagesCat. No.: HY-W046346CAS No.: 826998-10-1D44 is a Plasmodium FKBP35 inhibitor that selectively inhibits the FKBD35 PPIase activity, with PPIase IC50 values of 132 nM and 125 nM for Plasmodium falciparum and Plasmodium vivax, respectively. D44 exhibits antiplasmodium activity and can be used in research related to infectious diseases.
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Diclofop
0 ImagesCat. No.: HY-121273CAS No.: 40843-25-2Synonyms: Dichlorfop acid; (±)-DiclofopDiclofop (Dichlorfop acid) is an acetyl-CoA carboxylase (ACC) inhibitor. Diclofop is also the major metabolite of the herbicide Diclofop-methyl (HY-136367). Diclofop exhibits antimalarial activity with an IC50 of 210 μM against P. falciparum.
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Closantel (Standard)
0 ImagesClosantel (Standard) is the analytical standard of Closantel. This product is intended for research and analytical applications. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
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Murayaquinone
0 ImagesCat. No.: HY-133093CAS No.: 100843-91-2Synonyms: PKF118-774Murayaquinone (PKF118-774) is a β-catenin/Tcf4 complex inhibitor with an IC50 of 2.4 μM. Murayaquinone is a nematicidal agent found in Streptomyces sp. AN140557.
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Ibuprofen sodium (Standard)
0 ImagesSynonyms: (±)-Ibuprofen sodium (Standard)Ibuprofen (sodium) (Standard) is the analytical standard of Ibuprofen (sodium). This product is intended for research and analytical applications. Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers.
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SDH-IN-24
0 ImagesCat. No.: HY-173264SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH). The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC50 for SDH is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields.
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Fudecalone
0 ImagesCat. No.: HY-N14622CAS No.: 162341-22-2Fudecalone is found in the strain of Penicillum sp. FO-2030. Fudecalone completely inhibits Eimeria Tenella, a coccidius resistant to Monesin (HY-N4302).
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Allopurinol riboside (Standard)
0 ImagesCat. No.: HY-101397RCAS No.: 16220-07-8Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active.
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Lupenone (Standard)
0 ImagesLupenone is an orally active lupine-type triterpenoid that can be isolated from Musa basjoo. Lupenone Lupenone plays a role through the PI3K/Akt/mTOR and NF-κB signaling pathways. Lupenone has anti-inflammatory, antiviral, antidiabetic and anticancer activities.
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Antimalarial agent 65
0 ImagesCat. No.: HY-184406Antimalarial agent 65 is an inhibitor of Plasmodium falciparum lysyl-tRNA synthetase (PfKRS1), with a pIC50 value of 6.9 against Plasmodium falciparum. Antimalarial agent 65 inhibits the growth of Plasmodium falciparum strains. Antimalarial agent 65 exhibits activity across multiple life cycle stages of the malaria parasite, including transmission-blocking activity. Antimalarial agent 65 can be used in malaria-related research.
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Flubenzimine
0 ImagesCat. No.: HY-119719CAS No.: 37893-02-0Flubenzimine is a cyclic amidine acaricide. Flubenzimine significantly reduces the levels of dopamine and its precursor dopa in Rhizoglyphus echinopus.
